非接触二次色散法测量人体血糖的初步研究

提出了一种测量血糖浓度的新方法——二次色散法，此方法采用低相干干涉仪来测量时间相干干涉信号，通过傅里叶变换和多项式拟合获得二次色散。初步测量了三种不同浓度的糖溶液在0．55μm到0．8μm之间的二次色散，实验结果发现随着血糖浓度的增加，二次色散也随之增加。研究证明该方法是一种潜在的无接触、无伤害在线探测人体血糖浓度的方法。为设计一种非接触、无伤害在线探测人体血糖浓度的光学医疗仪器奠定基础。最后讨论了采用本方法尚需改进的问题和进一步的工作。

Preliminary Investigation of Second-Order Dispersion for Noninvasively Measuring Glucose Concentration in Human Body

A possibility to measure glucose concentration using a Michelson partial coherent interferometer (LCI) is presented. For three different glucose concentrations, 0.18 mg/mL (hypoglycemia), 0.95mg/mL (normal level) and 3.36 mg/mL (hyperglycemia) the second-order dispersion is investigated over the wavelength range 0.5 μm to 0.85 μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55 μm to 0.8 μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be expected as a potentially noninvasive method to measure glucose concentration in human body.