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压电免疫传感器的设计及应用
引用本文:周康源,王君,陈昕,叶为全,刘胜,鲍继鹏.压电免疫传感器的设计及应用[J].应用声学,2000,19(5):10-14.
作者姓名:周康源  王君  陈昕  叶为全  刘胜  鲍继鹏
作者单位:1. 中国科学技术大学合肥 230027
2. 解放军105医院检验科合肥 230031
摘    要:压电免疫传感器作为一种新型生物传感器,是利用压电元件的质量敏感性质,结合生物免疫识别特性而形成的一种自动化分析检测传感器,它可对钦种抗原或抗体进行的定量测定,并可有于反应动力学的研究,具有高特异性、高灵敏度、响应快、小型简便等特点。本文利用石英晶体产生体波厚度剪切振动模式,由双通道系统进行频率变化的测定。采用氨基硅烷膜固定抗体来定量检测溶液中人体免疫球蛋白Idisplay status

关 键 词:压电免疫传感器  抗体  人体免疫球蛋白  IgG  检测

The design and application of piezoimmunosensor
ZHOU Kang-yuan,WANG Jun,CHEN Xin,YE Wei-quan,LIU Sheng and BAO Ji-peng.The design and application of piezoimmunosensor[J].Applied Acoustics,2000,19(5):10-14.
Authors:ZHOU Kang-yuan  WANG Jun  CHEN Xin  YE Wei-quan  LIU Sheng and BAO Ji-peng
Institution:105 Hospital of PLA Hefei 230031;105 Hospital of PLA Hefei 230031;105 Hospital of PLA Hefei 230031;105 Hospital of PLA Hefei 230031;105 Hospital of PLA Hefei 230031;105 Hospital of PLA Hefei 230031
Abstract:Piezoimmunosensor is a new type of biosensor that utilizes the mass sensing characteristics of the piezoelectric material, connected to the biological immunosensing element. It forms a kind of automatic analytical sensor and is developed for a rapid quantitative analysis of multi antigens, antibodies and also for the study of reaction kinetics. It provides properties of high specificity, sensitivity, rapid response, minitype and simplicity. In this paper, a quartz crystal is used to produce bulk wave lating in the thickness shear mode, utilizing the dual channel to detect the relevant frequency shift. When we immobilize antibody with aminosaline film for the quantitative measurement of human mmunoglobulin IgG.
Keywords:Piezoimmunosensor  Bulk wave  Antibody  Human immunoglobulin  
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