| 表面活性剂增敏阻抑反应动力学光度法测定痕量铂 |
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| 引用本文： | 李建平,王雪燕.表面活性剂增敏阻抑反应动力学光度法测定痕量铂[J].光谱学与光谱分析,2000,20(3):443-445. |
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| 作者姓名： | 李建平 王雪燕 |
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| 作者单位： | 桂林工学院应用化学系,541004,桂林 |
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| 摘 要： | 研究了在硫酸介质中 ,在乳化剂 OP存在下 ,痕量铂 ( )阻抑溴酸钾氧化酸性品红褪色的新指示反应 ,建立了表面活性剂增敏阻抑反应动力学光度法测定痕量铂新方法。最大吸收波长为 5 44 nm。铂浓度在 0～ 2 .2 μg· L- 1范围内与ΔA呈线性关系 ,检测限为 0 .0 6 μg· L- 1。方法灵敏度高、选择性好、操作简便 ,用于抗癌药物顺铂及患者血清中铂含量的测定 ,取得较好的结果。
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| 关 键 词： | 乳化剂OP 动力学光度法 铂 顺铂 抗癌药物 |
Surfacant Sensitizing Kinetic Spectrophotometric Determination of Trace Platinum |
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| Jianping LI,Xueyan WANG.Surfacant Sensitizing Kinetic Spectrophotometric Determination of Trace Platinum[J].Spectroscopy and Spectral Analysis,2000,20(3):443-445. |
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| Authors: | Jianping LI Xueyan WANG |
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| Institution: | Department of Applied Chemistry, Guilin Institue of Technology, 541004 Guilin. |
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| Abstract: | A new kinetic spectrophotometric method for the determination of trace amount of platinum sensitizing by surfacant of emolsifier OP was proposed. It is based on the inhibition effect of platinum (IV) on the oxidizing decoloration of acid fuchsin by potassium bromate in 0.1 mol.L-1 sulphuric acid medium. The linear range for the determination of platinum is 0-2.2 micrograms.L-1. The detection limit is 0.06 microgram.L-1. Several parameter of the kinetic reaction were determined. The method is sensitive, selective and simple. It has been applied to the determination of trace platinum in chemotherapeutic drug cisplatin and serum from patients with satisfactory results. |
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| Keywords: | Sufacant Platinum Kinetic spectrophotometry Inhibition Cisplatin |
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