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利用近红外光谱检测多层组织血氧饱和度的研究
引用本文:高博,魏蔚,龚敏,王丽.利用近红外光谱检测多层组织血氧饱和度的研究[J].光谱学与光谱分析,2009,29(11):2922-2925.
作者姓名:高博  魏蔚  龚敏  王丽
作者单位:1. 四川大学物理科学与技术学院,微电子技术四川省重点实验室,四川,成都,610064
2. 四川大学华西医院麻醉与危重病医学教研室,四川,成都,610041
基金项目:国家自然科学基金项目 
摘    要:利用近红外光谱无创检测生物组织血氧饱和状态,是一种极富研究和应用前景的检测技术,在临床检测中被广泛应用.但常规临床检测应用于指端仅反映局部血氧饱和度信息,在使用中具有局限性,信号的可信度也存在质疑.该文提出了一种采用反射式脉搏血氧饱和度检测技术检测生物多层组织氧合状况的新方法,该方法通过调节入射光强以适应解剖学中生物组织多层结构的检测.应用该方法针对手指结构的实验结果表明,随着入射光强的改变,反映血氧饱和状态的光电脉搏波信号有显著变化.结合手指解剖学分析表明,光电脉搏波信号的变化与手指的多层面组织结构相对应,反映不同层面血氧饱和状态.这一特点表明,通过此法可以针对生物组织的多层结构进行测量.

关 键 词:多层组织  光电脉搏波信号  血氧饱和度  近红外光谱
收稿时间:2008/11/18

Near-Infrared Spectral Study on Blood Oxygen Saturation in Multilayer Tissue
GAO Bo,WEI Wei,GONG Min,WANG Li. School of Physical Science , Technology,Sichuan University,Sichuan Province Key Laboratory of Microelectronics,Chengdu ,China.Near-Infrared Spectral Study on Blood Oxygen Saturation in Multilayer Tissue[J].Spectroscopy and Spectral Analysis,2009,29(11):2922-2925.
Authors:GAO Bo  WEI Wei  GONG Min  WANG Li School of Physical Science  Technology  Sichuan University  Sichuan Province Key Laboratory of Microelectronics  Chengdu  China
Institution:GAO Bo1,WEI Wei2,GONG Min1,WANG Li21. School of Physical Science and Technology,Sichuan University,Sichuan Province Key Laboratory of Microelectronics,Chengdu 610064,China2. Department of Anesthesiology and Critical Ill Medicine,West China Hospital,Chengdu 610041,China
Abstract:The technology of non-invasive near-infrared spectral detection of biological tissue blood oxygen saturation has great research and application prospects,and has widespread clinical applications. However,the conventional finger oximeter only reflects local oxygen saturation values,and has limitations in the application. These oxygenation readings become unreliable or cease,too. In the present paper,a new method is described that the reflectance pulse oximetry with variable incident light intensity is employ...
Keywords:Multi-layer tissue  Photoplethysmographic signal  Blood oxygen saturation  Near-infrared spectrum  
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