益智红外指纹图谱的研究

益智产区的鉴别对于药材市场的质量控制以及提高药材的质量显得极为重要。益智为我国四大南药之一,主要药效成分是诺卡酮和益智酮。红外指纹图谱用于中药质量控制研究有着良好的发展前景,借助红外光谱的指纹特性,以八种益智精油红外指纹图谱的共有峰率和变异峰率为指标,计算了样品相对于该标准品的共有峰率和变异峰率,并按照共有峰率、变异峰率的大小建立了不同的序列。结果表明:广东、广西和海南的益智油红外图谱比较吻合,但也存在一定的差异。益智油的红外图谱特征峰为1 710和1 666cm-1,广东和海南的益智油的红外指纹图谱(400～4 000 cm-1)共有峰率为62%,广西和海南的共有峰率为52%,海南的益智油共有峰率为66%～84%。从多维共有峰率和变异峰率双指标序列分析法可以对不同产地具有准确、精细且非常直观的鉴别能力,该方法可以准确地区别不同产地的益智。

Study on IR Fingerprint Spectra of Alpinia Oxyphylla Miq

Fourier transform infrared spectrum has been developed for application in the quality control of traditional Chinese medicine,and two new indexes,including common peak ratio and variant peak ratio,were applied,and their values were calculated by means of the sequential analysis for eight kinds of essence oil of Alpinia oxyphylla Miq from different cultural areas(Hainan,Guangxi and Guangdong),in which each sample's IR fingerprint spectra were set up and the common peak ratio and variant peak ratio sequences were arranged in the order of size in comparison with other samples.It can be seen that Alpinia oxyphylla samples from Guangxi,Hainan and Guangdong provinces could be successfully revealed directly by the common peak ratio and variant peak ratio sequences.In comparison with their conventional IR spectra,the primary difference in Alpinia oxyphylla is the intensity of characteristic peaks at 1 710 and 1 666 cm-1.Considering the spectral range of 400-4 000 cm-1,the common peak ratio of the spectra between Hainan and Guangdong was 62%,while the common peak ratio between Hainan and Guangxi was 52%.But the mix common peak ratio of the spectra in Hainan is 66%.The fingerprint characters of IR can not only identify the main chemical constituents in medicinal materials,but also compare the components differences among the similar samples.The analytical method is an rapid,effective,fast and advanced to evaluate the production area for pharmaceutical market.