宫颈正常与宫颈癌组织傅里叶变换红外光谱的初步研究

利用傅里叶变换红外光谱对宫颈鳞癌(17例)、宫颈腺癌(5例)及宫颈正常组织(13例)进行了分析。结果显示，18个谱带在各类组织中的出现概率都在80%以上，显示其在组织中的特征性;这3类组织红外光谱的相对吸收峰吸光度差异主要表现在1 080，1 238，1 314，1 339，1 397，1 454，1 541，1 647，2 854， 2 873，2 926和2 958 cm-1处的比较上。傅里叶变换红外光谱仪可用于区分宫颈鳞癌、腺癌及宫颈正常组织，以该仪器为基础的方法有望成为宫颈癌筛检及临床诊断的新方法。

Fourier Transform Infrared Spectroscopy Study on Normal and Malignant Tissues of Cervix

Fourier transform infrared spectroscopy(FTIR) was used to investigate 35 cervical tissues,including 17 squamous cell carcinoma of cervical samples,and 5 adenocarcinoma of cervical samples,13 normal cervical samples.The results show that there are 18 spectral bands with highly appearance percentage(>80%)in these three types of tissues,and these spectral bands may be the characteristic infrared spectra bands for cervical tissues;Some of relative absorbance ratios are statistically significant(p<0.05) among these three types of tissues.These differences of relative absorbance ratios are mainly centered at 1 080,(1 238,) 1 314,1 339,1 397,1 454,1 541,1 647,2 854,2 873,2 926,and 2 958 cm~(-1).The present results indicate that FTIR can be used to distinguish these three types of tissues.The utilization of FTIR spectra in cervical tissues is expected to be a hopeful method in cervical cancer screening and clinical diagnosis in the future.