应用红外光谱技术鉴别中药麝香的真伪

采用傅里叶变换红外(FTIR)光谱法并结合二阶导数技术,测定了中药天然麝香及其伪品的红外光谱.结果表明:天然麝香的主要特征峰为3 284,2 923,2 851,1 655,1 546,1 400,1 038 cm-1等吸收峰,分别代表蛋白质、大环酮类和甾体类等主要成分;与天然麝香相比,麝香伪品的红外光谱的吸收的位置和强度有明显差异,可被容易区分;天然麝香、市售麝香及人工麝香的谱图相似性较高,尤其是人工麝香与天然麝香极其相似,难以区分;采用傅里叶二阶导数谱,提高了谱图分辨率,可直观有效地鉴别正品麝香.该方法具有快速、灵敏、直观、无损等特点,可为名贵药材的来源与真伪鉴别提供了新的手段.

Identification of musk by Fourier transform infrared spectroscopy

Standard nature musk and false nature musk were identified by Fourier transform infrared spectroscopy (FTIR) combined with derivative spectra in the present article. The main characteristic absorption peaks of musk represented the key components such as macrocyclic ketone (2923, 2851 cm(-1)), polypeptides (1655, 1546 cm(-1)) and steroids (1400, 1038 cm(-1)) respectively. Ensuing from the researches artificial musk and natural musk resemble the exemplar of market nature musk. Particularly, the infrared spectra of samples of natural musk and artificial musk are more similar and hard to be distinguished. In virtue of derivative spectra analysis, the resolution of spectra is advanced; several kinds of standard musk have been differentiated directly and effectively. This method was fast, sensitive, direct and nondestructive, and could be used to identify the source of rare materia medica and distinguish the counterfeits of musk successfully.