同步扫描荧光光谱法同时测定阿司匹林和水杨酸

建立了同步扫描荧光光谱法单次扫描同时测定阿司匹林和水杨酸双组分的方法。荧光光度计同步扫描时，得到两组分互不干扰的荧光峰，借此分别测定两组分的含量。阿司匹林和水杨酸浓度分别在4.0×10-6～1.0×10-4 mol·L-1, 8.0×10-7～1.0×10-4 mol·L-1范围内与荧光强度呈线性关系，相关系数分别为0.994 9和0.997 5，水杨酸的检测限为4.0×10-7 mol·L-1。该法简单、快速准确、易操作，可用于药物制剂中阿司匹林和水杨酸的同时测定。

Simultaneous Determination of Aspirin and Salicyclic Acid by Synchronous Fluorescence Spectrometry

A simple, rapid and inexpensive fluorimetric method for simultaneously determining ASA and SA in a single scan of the co-existing specimen had been established. When the wavelength interval (delta lambda) is 80 nm for scaning, the amounts of ASA and AS could be quantitatively determined respectively. The fluorescence intensity was linearly related to the aspirin concentration in the range of 4.0 x 10(-6)-1.0 x 10(-4) mol x L(-1) with correlation coefficient 0.9949; the fluorescence intensity was linearly related to the salicyclic acid concentration in the range of 8.0 x 10(-7)-1.0 x 10(-4) mol x L(-1) with correlation coefficient 0.9975, the determination limit was 4.0 x 10(-7) mol x L(-1). The method is simple, rapid and inexpensive, it can be used for medicament analysis.