| 胃肠道正常组织与相应肿瘤组织结构的FTIR光谱研究 |
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| 引用本文： | 彭卿,徐怡庄.胃肠道正常组织与相应肿瘤组织结构的FTIR光谱研究[J].光谱学与光谱分析,1998,18(5):528-531. |
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| 作者姓名： | 彭卿 徐怡庄 |
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| 作者单位： | [1]北京航空材料研究院 [2]北京大学化学与分子工程学院 |
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| 基金项目： | 国家自然科学基金,国家攀登计划和国家教委博士点基金 |
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| 摘 要： | 本文用傅里叶变换红外显微光谱对一系列胃肠道（食道、胃、结肠）肿瘤组织和相应正常组织的冰冻切片进行了研究。结果显示，所有肿瘤组织的光谱基本一致。而正常组织的光谱按１４００－９５０ｃｍ＾－１区域的特点可分为三类。对光谱中蛋白质酰胺Ｉ带曲线拟合的结果表明，正常组织和肿瘤组织中蛋白质的二级结构有着很大的差别。
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| 关 键 词： | 肿瘤组织 FTIR 切片 胃肠道组织 二级结构 |
FTIR STUDY ON THE NORMAL AND TUMOR GASTROINTESTINAL TISSUES |
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| Q Peng,Y Xu,W Li,J Wu,X Zhou.FTIR STUDY ON THE NORMAL AND TUMOR GASTROINTESTINAL TISSUES[J].Spectroscopy and Spectral Analysis,1998,18(5):528-531. |
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| Authors: | Q Peng Y Xu W Li J Wu X Zhou |
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| Institution: | Beijing Institute of Aeronautical Materials, 100095 Beijing. |
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| Abstract: | Series of cancer tissues and corresponding normal tissues of gastrointestinal tract (stomach, colon, esophagus) were studied by FTIR technique and the results showed the analogy of the spectra for the cancer tissues, while the spectra of normal tissues can be classified into three kinds. The secondary structures of protein were obtained by using deconvolution and curve-fitting techniques with Amide I bands and the results showed that the contents of alpha -helix and beta-sheet are different between the normal and cancer tissues. |
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| Keywords: | Tumor FTIR Frozen section Gastrointestinal tract Secondary structure of protein |
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