分子振动光谱法与中药研究的最新进展

本文叙述了分子振动光谱法（傅半叶变换拉曼光谱技术和傅立叶变换红外光谱技术）的量新发展与中药的无损定性鉴别、定量分析、热稳定性监控及中药优化的最新应用。报道了利用傅立叶变换拉曼光谱技术（ＦＴ－Ｒａｍａｎ）和漫反射傅立叶变换２红外光谱技术（ＤＲ－ＦＴＩＲ）可以直接快速地鉴别生药材；利用漫反射傅立叶变换近红外光谱技术（ＤＲ－ＮＩＲ）可以无损定量分析中药材、中成药和方剂的组分含量利用ＦＴ－Ｒａｍａｎ和ＨＡ

The Latest Development of the Research on Chinese Medicine by Molecular Vibrational Spectroscopy

The latest development of the molecular vibrational spectroscopy (Fourier Transform Raman Spectroscopy and Fourier Transform Infraed Spectroscopy) and the latest application of the non destructive identification,quantitative analysis,thermal stability monitoring and Chinese medicine optimizing were described in this paper.Some Chinese crude herbs can be directly and quickly identified by Fourier Transform Raman Spectroscopy (FT Raman) and Diffused Reflection Fourier Transform Infrared Spectroscopy (DR FTIR). The content of Chinese herbs,medicine and medicament can be quantified without destruction by Diffused Reflection Fourier Transform and Near Infrared Spectroscopy (DR NIR FTIR).The mechanism of interaction between the Chinese medicine and some cells or bacteria can be in situ monitored by FT Raman and HATR FTIR.Best medicine could be selected and medicament could be optimized according to the injury degree of the cell or bacteria.The decomposing and degenerating process of medicines can also be timely monitored by FT Raman and the temperature controlled FTIR.These are the latest use of molecular spectroscopy in Chinese medicine.The fast identification,quantitative analysis monitoring,thermal stability predicting and the optimizing of Chinese herbs,medicine and medicament can be guided by the above mentioned methods.It is proved that these methods are nondestructive to samples,fast accurate,and easy to use.