| 直肠癌组织与直肠正常组织的荧光光谱研究 |
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| 引用本文： | 孟涛,徐端夫,徐怡庄,赵莹,王笃金,吴瑾光.直肠癌组织与直肠正常组织的荧光光谱研究[J].光谱学与光谱分析,2007,27(6):1156-1160. |
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| 作者姓名： | 孟涛 徐端夫 徐怡庄 赵莹 王笃金 吴瑾光 |
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| 作者单位： | 1.中国科学院化学研究所，高分子物理与化学国家重点实验室，北京 100080
2.北京大学化学与分子工程学院，北京 100871 |
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| 基金项目： | 国家重点基础研究发展计划(973计划)
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国家自然科学基金 |
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| 摘 要： | 用荧光光谱仪对12例离体直肠癌组织和对应的直肠正常组织的荧光光谱(激发光的波长为320 nm)进行了研究。并与相应的红外光谱结果进行了对比。结果表明直肠正常组织的荧光强度明显高于直肠癌组织的荧光强度。直肠组织在波长为492和544 nm的荧光强度的差别可用于区分直肠正常和直肠癌组织。
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| 关 键 词： | 直肠癌 最佳激发波长 荧光光谱 诊断 |
| 文章编号： | 1000-0593（2007）06-1156-05 |
| 收稿时间： | 2006-10-28 |
| 修稿时间： | 2006-10-282007-02-02 |
Investigation on the Fluorescence Spectroscopy of Normal and Malignant Rectum Tissues |
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| MENG Tao,XU Duan-fu,XU Yi-zhuang,ZHAO Ying,WANG Du-jin,WU Jin-guang.Investigation on the Fluorescence Spectroscopy of Normal and Malignant Rectum Tissues[J].Spectroscopy and Spectral Analysis,2007,27(6):1156-1160. |
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| Authors: | MENG Tao XU Duan-fu XU Yi-zhuang ZHAO Ying WANG Du-jin WU Jin-guang |
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| Institution: | 1. State Key Laboratory of Polymer Physics and Chemistry, Joint Laboratory of Polymer Science and Materials, Institute of Chemistry, the Chinese Academy of Sciences, Beijing 100080, China2. College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China |
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| Abstract: | In the present article the fluorescence characteristics of normal and malignant rectum organ tissues of 12 samples were investigated in vitro using UV(200-400 nm) fluorescence spectroscopy and compared with the results of the infrared spectra of normal and malignant rectum organ tissues.The results showed that the fluorescence intensity of normal rectal tissue was higher than that of rectal malignant tissue.The difference in fluorescence intensity at 492 and 544 nm between normal rectal tissue and malignant tissue may be considered as a detection criterion. |
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| Keywords: | Rectal cancer Optimal excitation wavelength Fluorescence spectra Diagnose |
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