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增生性疤痕组织与正常上皮组织FTIR光谱研究
引用本文:东野广智,孟庆勇,张培华,汤少明,周群,孙素琴,胡鑫尧.增生性疤痕组织与正常上皮组织FTIR光谱研究[J].光谱学与光谱分析,2003,23(2):270-272.
作者姓名:东野广智  孟庆勇  张培华  汤少明  周群  孙素琴  胡鑫尧
作者单位:1. 广东医学院分析中心,广东,湛江,524023
2. 广东医学院附属医院整形外科,广东,湛江,524001
3. 清华大学化学系,北京,100084
摘    要:通过对40例疤痕组织和正常皮肤组织的ETIR光谱比较分析发现,由于个体差异,其光谱均可分为三种不同类型。此外,疤痕组织中的胶原、蛋白质、核酸和脂类等生物大分子的吸收峰强度均在不同程度上高于正常皮肤组织,但两者的A_(1083)/A_(1548)并无明显差异。提示疤痕组织中的细胞仍属正常生长,治疗中不应损伤。

关 键 词:增生性疤痕  傅里叶变换红外光谱法
文章编号:1000-0593(2003)02-0270-03
修稿时间:2002年8月20日

FTIR Study on the Hypertrophicscar and Normal Skin Tissues
DONYE Guang-zhi,MENG Qing-yong,ZHANG Pei-hua,TANG Shao-ming,ZHOU Qun,SUN Su-qin and HU Xin-rao . Anlysis Center,Guangdong Medical College,Zhanjiang ,China.FTIR Study on the Hypertrophicscar and Normal Skin Tissues[J].Spectroscopy and Spectral Analysis,2003,23(2):270-272.
Authors:DONYE Guang-zhi  MENG Qing-yong  ZHANG Pei-hua  TANG Shao-ming  ZHOU Qun  SUN Su-qin and HU Xin-rao Anlysis Center  Guangdong Medical College  Zhanjiang  China
Institution:Anlysis Center, Guangdong Medical College, Zhanjiang 524023, China.
Abstract:40 cases of hypertrophicscar (HS) tissues and corresponding normal skin tissues were studied by FTIR technique, and the results snowed that all of the HS and normal tissues can be classified into three kinds. Furthermore, the absorption bands of biomacro-molecule in collagen, protein, nucleic acid and lipid of hypertrophicscar are stronger than those of normal tissues. But there is no significant difference in A1083/A1548 between HS and normal tissues. It is suggested that the cells of HS could still be normally growing and should not be scathed in the treatment process.
Keywords:Hypertrophic scar  FTIR
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