| 抗菌素阿莫西林荧光分析法的研究 |
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| 引用本文： | 马丽花,陈亮,黄淑萍.抗菌素阿莫西林荧光分析法的研究[J].光谱学与光谱分析,1999,19(2):230-232. |
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| 作者姓名： | 马丽花 陈亮 黄淑萍 |
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| 作者单位： | 山西大学分析测试中心,030006,太原 |
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| 基金项目： | 山西省留学回国人员科研项目 |
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| 摘 要： | 本文提出了阿莫西林（２Ｓ，５Ｒ，６Ｒ）－３，３－二甲基－６（Ｒ－）－（１）－２－氨基２－（４－羟基苯基）乙酰氨基－７氧化－４－硫杂－１氮杂双环（３，２，０）庚烷－２－甲酸三水化合物荧光分析的方法。并对影响阿莫西林荧光性质（光谱和光谱强度）的各种因素，包括ｐＨ值、表面活性剂的增效作用、无机离子的配合作用以其他介质条件等进行了较为详细的研究。实验结果表明，阿莫西林具有良好的荧光性质，在微碱性条件下荧光
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| 关 键 词： | 阿莫西林 荧光分析法 |
Fluorescence Studies on Amoxicillin |
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| Lihua MA,Liang CHEN,Shuping HUANG.Fluorescence Studies on Amoxicillin[J].Spectroscopy and Spectral Analysis,1999,19(2):230-232. |
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| Authors: | Lihua MA Liang CHEN Shuping HUANG |
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| Institution: | Test and Analysis Center of Shanxi University, 030006 Taiyuan. |
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| Abstract: | The effects of pH, various organic solvents such as acetone, methanol, ethanol, surface-active agent on amoxicillin have been studied in detail. Put in pH=8 buffer solution, amoxicillin has strong fluorescence emission, excitaion wavelength of 277 nm, and emission wavelength of 303 nm. Calibration curve of amoxicillin was linear between 2 x 10(-5) and 2 x 10(-4) mol/L, with a regression coefficient of 0.9996. CTAB can enhance its fluorescence intensity. The results of fluorescence spectra of amoxicillin added with metal ions (Mg2+, Ca2+, Al3+, Ga3+) at pH=12 showed that there are interactions between amoxicillin and metal ions. |
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