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Two-dimensional model of elastically coupled molecular motors
Authors:Zhang Hong-Wei  Wen Shu-Tang  Chen Gai-Rong  Li Yu-Xiao  Cao Zhong-Xing and Li Wei
Institution:School of Physics and Engineering, Zhengzhou University, Zhengzhou 450052, China;Department of Physics, Zhengzhou Normal University, Zhengzhou 450044, China;School of Physics and Engineering, Zhengzhou University, Zhengzhou 450052, China;School of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453003, China;School of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453003, China;School of Physics and Engineering, Zhengzhou University, Zhengzhou 450052, China;School of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453003, China;School of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453003, China
Abstract:A flashing ratchet model of a two-headed molecular motor in a two-dimensional potential is proposed to simulate the hand-over-hand motion of kinesins. Extensive Langevin simulations of the model are performed. We discuss the dependences of motion and efficiency on the model parameters, including the external force and the temperature. A good qualitative agreement with the expected behavior is observed.
Keywords:Brownian motors  ratchet  current  efficiency
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