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| 两种非球形细胞光镊阱力标定方法的比较 | |
| 引用本文： | 喻有理,张镇西,贾蕊,严秋劳.两种非球形细胞光镊阱力标定方法的比较[J].光子学报,2006,35(3):394-397. |
| 作者姓名： | 喻有理 张镇西 贾蕊 严秋劳 |
| 作者单位： | 1. 西安交通大学,生物医学信息工程教育部重点实验室,生物医学工程研究所,西安,710049;西安交通大学理学院,西安,710049 2. 西安交通大学,生物医学信息工程教育部重点实验室,生物医学工程研究所,西安,710049 3. 西安交通大学能源与动力工程学院,西安,710049 |
| 基金项目： | Supported by the National Natural Science Foundation of China（No. 60378018） |
| 摘 要： | 玻尔兹曼统计法和均方位移法是两种可用于对非球型生物细胞在简谐光势阱中光阱力的标定方法. 用数字实验对这两种标定方法进行了比较, 结果表明： 与均方位移法相比，玻尔兹曼统计法不仅适用于各向异性非球性细胞，也适用于非简谐、非对称光势阱中任意形状的生物细胞光阱力的标定，结论与已有直接实验相符. |
| 关 键 词： | 玻尔兹曼分布 光镊 光阱刚度 生物细胞 |
| 收稿时间： | 2005-08-07 |
| 修稿时间： | 2005年8月7日 |
Compare for Calibration Methods to Optical Trapping Force Upon Non-spherical Biological Cells |
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| Yu Youli,Zhang Zhenxi,Jia Rui,Yan Qiulao.Compare for Calibration Methods to Optical Trapping Force Upon Non-spherical Biological Cells[J].Acta Photonica Sinica,2006,35(3):394-397. | |
| Authors: | Yu Youli Zhang Zhenxi Jia Rui Yan Qiulao |
| Institution: | 1 The Key Laboratory of Biomedical Information Engineering of Ministry of Education,Institute of Biomedical Engineering, Xi′an Jiaotong University, Xi′an 710049 2 School of Science. Xi′an Jiaotong University , Xi’an 710049 3 School of Energy and Power Engineering .Xi′an Jiaotong University,Xi’an 710049 |
| Abstract: | Both Boltzmann distribution method(BDM) and mean square displacement method(MSDM)are available for the force calibration of non-spherical biological cells in a harmonic optical trap. These two calibration methods were compared with numeric experiments. Results indicate that comparing with MSDM, BDM is not only available for the force calibration of non-spherical or anisotropic cells, but also for irregular cells in optical trap potential with inharmonic and asymmetric profiles.The results agree with the experiments reported. |
| Keywords: | Boltzman distribution Optical tweezers Trapping stiffness Biological cells |
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