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光学相干层析成像色散补偿研究
引用本文:林林,高应俊,龙炳昌,蔡里禹,何永健.光学相干层析成像色散补偿研究[J].光子学报,2014,39(6):1099-1103.
作者姓名:林林  高应俊  龙炳昌  蔡里禹  何永健
作者单位:(1 暨南大学 光电信息与传感技术广东普通高校重点实验室,广州 510632)
(2 暨南大学 理工学院 光电工程系,广州 510632 )
(3 广东医学院 生物医学工程教研室,东莞 523808)
摘    要:针对通过增加光源谱宽度来提高光学相干层析成像系统分辨率时样品色散特性的限制作用,分析了色散与光学相干层析成像系统纵向光程分辨率的约束关系.根据物质色散特性,采用数值变换方法对光学相干层析成像相干成像信号进行了色散补偿.实验使用了中心波长1 550 nm 自激发辐射光源和光纤迈克尓逊干涉结构,对水和光学快速扫描延迟线引入的二阶和三阶色散进行了数值补偿并通过相位修正因子来改善补偿效果.确定了一种普适的、快速的数值色散补偿方法.在对水中盖玻片和生物组织和的光学相干层析成像图像的色散补偿实验中取得了良好的效果,证明了方法的可行性.

关 键 词:医用光学与生物技术  色散补偿  快速傅里叶变换  光学相干层析
收稿时间:2009-09-18

Dispersion Compensation in Optical Coherence Tomography
LIN Lin,GAO Ying-Jun,LONG Bing-Chang,CAI Li-Yu,HE Yong-Jian.Dispersion Compensation in Optical Coherence Tomography[J].Acta Photonica Sinica,2014,39(6):1099-1103.
Authors:LIN Lin  GAO Ying-Jun  LONG Bing-Chang  CAI Li-Yu  HE Yong-Jian
Institution:(1 Key Laboratory Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes,
Jinan University,Guangzhou 510623,China)
(2 Department of Optoelectronic Engineering,Jinan University,Guangzhou 510623,China )
(3 Department of Biological Engineering,Guangdong Medical College,Dongguan,Guangdong 523808,China)
Abstract:In order to solve the problem that dispersion in dispersive material restricts improvement of depth resolution of optical coherence tomography(OCT)with broadband optical source.a numerical posteriori dispersion compensation technique for optical coherence tomography depth-scan signals is presented.The relationship between resolution of optical coherence tomography and FWHM of optical source is analyzed.In experience,1 550 nm optical source and fiber Michelson interferometer are used to get imaging signal from planes in the water.Data of the image are compensated up to the third order optical dispersion of water and rapid optical delay line.A tunable phase factor is introduced to improve the results of compensation.Examples of dispersion compensated depth-scan signals obtained from microscope cover glasses under  water and muscle tissue of mouse are presented.
Keywords:Medical optics and biotechnology  Dispersion compensation  Fast Fourier Transform(FFT)  Optical Coherence Tomography(OCT)
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