| 基于复合纳米结构的局域表面等离子体光学传感器 |
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| 引用本文： | 杨欢,李飞,罗先刚,蔡冬梅,刘娟意,马文英.基于复合纳米结构的局域表面等离子体光学传感器[J].光学与光电技术,2010,8(2):80-83. |
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| 作者姓名： | 杨欢 李飞 罗先刚 蔡冬梅 刘娟意 马文英 |
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| 作者单位： | 中国科学院光电技术研究所微细加工光学技术国家重点实验室,四川,成都,610209 |
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| 摘 要： | 局域表面等离子体光学传感器由于其体积小、灵敏度高、免标记等特点成为目前传感器研究热点之一。然而由于银纳米结构的生物兼容性以及氧化问题，成为该传感器发展的瓶颈。提出了利用金／银混合的金属纳米结构克服上述困难，并从有限时域差分数值计算方法入手，设计了银层50nm，金层5nm的六边形分布三角形复合传感结构，并利用纳米球自组装技术实现了该类型传感器。同时，与生物分子蛋白A的结合实验结果表明，该传感器在生物分子溶液浓度213．85nM的条件下仍然具有较高的灵敏度。
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| 关 键 词： | 局域表面等离子体传感 复合纳米结构 消光光谱 表面等离子体共振 |
Localized Surface Plasmonic Biosensor Based on Composite Nanostructures |
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| YANG Huan,LI Fei,LUO Xian-gang,CAI Dong-mei,LIU Juan-yi,MA Wen-ying.Localized Surface Plasmonic Biosensor Based on Composite Nanostructures[J].optics&optoelectronic technology,2010,8(2):80-83. |
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| Authors: | YANG Huan LI Fei LUO Xian-gang CAI Dong-mei LIU Juan-yi MA Wen-ying |
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| Institution: | ( State Key I.ab of Optical Technologies for Microfabrication, Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu 610209, China ) |
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| Abstract: | It is well known that the localized surface plasmon resonance（LSPR） biosensor based on Ag nanotriangles is widely used due to its high sensitivity. However, such biosensor can only be stored for a short time because the Ag nanostruclures are chemically instable and biologically incompatible. In this paper, the sensitivity of composite gold-silver LSPR sen sors for stable performance is studied by using finite difference time domain （FDTD）. It＇s shown that the optimal configuration for such composite I.SPR sensor should be gold（5 nm）-silver（40 nm） for comparable sensitivity to traditional Ag LSPR sensor. With the detection of target molecule （Protein A）, and such sensor can response under concentration of 213. 85 nM. |
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| Keywords: | localized surface plasmon sensing composite nanostructure extinction spectra surface plasmon resonance |
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