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Multi-objective optimization of inverse planning for accurate radiotherapy |
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| Authors: | CAO Rui-Fen WU Yi-Can PEI Xi JING Jia LI Guo-Li CHENG Meng-Yun LI Gui HU Li-Qin |
| Institution: | CAO Rui-Fen1,2 WU Yi-Can1,2,3 PEI Xi1,2 JING Jia1,3,5 LI Guo-Li4 CHENG Meng-Yun1,2 LI Gui1,2 HU Li-Qin1,2 1 Institute of Plasma Physics,Chinese Academy of Sciences,Hefei 230031,China 2 Engineering Technology Research Center of Accurate Radiotherapy,China 3 School of Nuclear Science and Technology,University of Science and Technology of China,Hefei 230027,China 4 Zhejiang University of Technology,Hangzhou 310014,China 5 Hefei University of Technology,Hefei 230009,China |
| Abstract: | The multi-objective optimization of inverse planning based on the Pareto solution set, according to the multi-objective character of inverse planning in accurate radiotherapy, was studied in this paper. Firstly, the clinical requirements of a treatment plan were transformed into a multi-objective optimization problem with multiple constraints. Then, the fast and elitist multi-objective Non-dominated Sorting Genetic Algorithm (NSGA-) was introduced to optimize the problem. A clinical example was tested using... |
| Keywords: | inverse planning multi-objective optimization accurate radiotherapy |
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