| 4(5)-氰基咪唑的合成与表征 |
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| 引用本文： | 梁倩倩,林原斌.4(5)-氰基咪唑的合成与表征[J].光谱实验室,2012,29(1):58-60. |
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| 作者姓名： | 梁倩倩 林原斌 |
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| 作者单位： | 湘潭大学化学学院环境友好化学与应用省部共建教育部重点实验室 411105 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 以D-果糖为初始原料,经环合、氧化,再加入盐酸羟胺作为氰基化试剂一步法制得4(5)-氰基咪唑.利用1H NMR、13C NMR等手段对各步所得产物的结构进行了表征,结果表明产物为4(5)-氰基咪唑.以D-果糖计,3步反应的总收率为33.5％.
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| 关 键 词： | 果糖 环合 氧化 氰基化 盐酸羟胺 |
Synthesis and Characterization of 1H-Imidazole-4-Carbonitrile |
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| LIANG Qian-Qian
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LIN Yuan-Bin.Synthesis and Characterization of 1H-Imidazole-4-Carbonitrile[J].Chinese Journal of Spectroscopy Laboratory,2012,29(1):58-60. |
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| Authors: | LIANG Qian-Qian LIN Yuan-Bin |
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| Institution: | (Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education, College of Chemistry,Xiangtan University,Xiangtan,Hunan 411105,P.R.China) |
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| Abstract: | 1H-Imidazole-4-carbonitrile were synthesized with D-fructose as starting materials by cyclization,oxidation and cyanation in a one-spet process by adding hydroxylamine hydrochloride.The structure of the compound was confirmed by 1H NMR,13C NMR etc.The target product was identified as 1H-imidazole-4-carbonitrile.The overall yield of fructose was 33.5%in three steps. |
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| Keywords: | Fructose Cyclization Oxidation Cyanation Hydroxylamine Hydrochloride |
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