电感耦合等离子体-质谱法快速测定尿铅含量

尿样用1% HNO3稀释50倍,并以209Bi为内标元素校准基体效应及信号漂移,用电感耦合等离子体-质谱法直接测定,外标法绘制校准曲线进行定量.分别用ICP-MS和双硫腙分光光度法测定同一批尿样中铅的含量,统计并比较两种方法的测定结果,结果经t检验差异无统计学意义.该方法测定尿样中铅的检出限为0.010mg/L,线性良...

Rapid Determination of Lead in Urine by Inductively Coupled Plasma-Mass Spectrometry

The samples were diluted as 50 times by 1% HNO3,and 209Bi was used as the internal standard element for calibration matrix effect and signal drift,that was directly determined by ICP-MS.The calibration curve was drew to quantitate the determinand by extemal standard methed.The content of lead in same batch of urine samples were determined by ICP-MS and dithizone spectrophotometry,respectively.The determination results were compared by statistics.The limit of detection for lead in urine was 0.010mg/L with good linear correlation（r=0.9997）.The relative standard deviation was 1.05%—4.88%,and recovery was 94.4%—106.8%.The samples were simultaneously determined by ICP-MS and dithizone spectrophotometry,and the difference had no statistical significance when the results were determined by t detection.This method was proved to be rapid,accurate and reliable with simple pretreatment of sample,high efficiency and low interference.It could be applied to the analysis of lead in large numbers of urine samples with satisfactory results.