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锥虫保护剂冻结及冻干特性研究
引用本文:王海燕,谭光平,吕树申,伦照荣.锥虫保护剂冻结及冻干特性研究[J].工程热物理学报,2011(8).
作者姓名:王海燕  谭光平  吕树申  伦照荣
作者单位:中山大学化学与化学工程学院;
基金项目:国家重大基础研究前期研究专项资金(No 2005CCA01400); 中山大学实验室开放基金项目(No.KF200919);中山大学2009青年教师起步资助计划项目
摘    要:保护剂溶液冻结及冻干特性的研究对生物材料保护剂的选择以及冷冻干燥工艺的设计具有重要的指导意义。选择聚乙烯醇(PVA)、海藻糖和叔丁醇作为锥虫的保护剂,采用差示扫描量热法研究了PVA/海藻糖/叔丁醇保护剂溶液的冻结特性,并对PVA/海藻糖/叔丁醇保护剂溶液进行了冷冻干燥实验,考察了不同冷冻条件对PVA/海藻糖/叔丁醇保护剂溶液冻结特性和冻干特性的影响。

关 键 词:保护剂  锥虫  冻结  冷冻干燥  

Study of Freezing and Freeze-Drying of the Protectants for Trypanosome
WANG Hai-Yan TAN Guang-Ping LShu-Shen LUN Zhao-Rong.Study of Freezing and Freeze-Drying of the Protectants for Trypanosome[J].Journal of Engineering Thermophysics,2011(8).
Authors:WANG Hai-Yan TAN Guang-Ping LShu-Shen LUN Zhao-Rong
Institution:WANG Hai-Yan TAN Guang-Ping L(U|¨)Shu-Shen LUN Zhao-Rong (School of Chemistry and Chemical Engineering,Sun Yat-Sen University,Guangzhou 510275,China)
Abstract:The study of freezing and freeze-drying of protectant solutions is of great importance for the selection of protectants and the design of freeze-drying processes for the freeze-drying of biomaterials.In the present study,polyvinyl alcohol(PVA),trehalose and tert-butanol were selected as protectants for the freeze-drying of trypanosome,and they were used to prepare the aqueous protectant solutions.The freezing behavior of the aqueous protectant solutions of PVA,trehalose and tert-butanol was investigated by ...
Keywords:protectant  trypanosome  freezing  freeze-drying  
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