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激光诱导间质热疗的深低温流体冷却方法
引用本文:邓中山,刘静.激光诱导间质热疗的深低温流体冷却方法[J].工程热物理学报,2008,29(2):294-296.
作者姓名:邓中山  刘静
作者单位:中国科学院理化技术研究所,北京,100080
基金项目:国家自然科学基金 , 中国科学院优秀博士学位论文获得者科研启动专项资金资助项目
摘    要:为防止激光诱导间质内热疗治疗肿瘤时激光光纤加热段周围组织的炭化,本文提出了一种采用深低温流体对激光光纤及其临近组织进行降温冷却的方法.为验证该方法的可行性,本文对采用该方法后激光间质内热疗过程中组织的传热问题进行了深入的数值研究.结果表明,深低温流体冷却方法可避免局部高温对组织的炭化,并显著扩展有效加热范围,从而对肿瘤实施高效的热凝固.

关 键 词:激光间质内热疗  肿瘤热疗  冷却方法  生物传热  激光诱导间质热疗  低温流体  冷却方法  THERMOTHERAPY  INTERSTITIAL  COOLING  METHOD  FLUID  热凝固  实施  治疗肿瘤  范围  加热段  扩展有效  高温  局部  结果  数值研究  传热问题  过程  验证
文章编号:0253-231X(2008)02-0294-03
修稿时间:2007年12月30

ULTRA-LOW TEMPERATURE FLUID COOLING METHOD FOR LASER-INDUCED INTERSTITIAL THERMOTHERAPY
DENG Zhong-Shan,LIU Jing.ULTRA-LOW TEMPERATURE FLUID COOLING METHOD FOR LASER-INDUCED INTERSTITIAL THERMOTHERAPY[J].Journal of Engineering Thermophysics,2008,29(2):294-296.
Authors:DENG Zhong-Shan  LIU Jing
Abstract:To avoid carbonization of tissues surrounding to the heating part of laser fiber during treating tumor by laser-induced interstitial thermotherapy(LITT),a new method using ultra-low temperature fluid was proposed for cooling laser fiber and tissues in the vicinity of laser fiber in this study.To test its feasibility,the corresponding bioheat transfer process applying this cooling method during LITT was studied through extensive numerical simulations.The results indicate that the cooling method by ultra-low temperature fluid can prevent carbonization of tissues resulted by local high temperature,significantly enlarge the effective heating area and thus actualize highly efficient thermal coagulation to tumor tissues.
Keywords:laser-induced interstitial thermotherapy  tumor hyperthermia  cooling method  bioheat transfer
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