A 32-channel coil system for MR vessel wall imaging of intracranial and extracranial arteries at 3T |
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| Institution: | 1. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology of Chinese Academy of Sciences, China;2. Shenzhen Key Laboratory for MRI, Shenzhen, China;3. Department of Radiology and Biomedical Imaging, University of California San Francisco, CA, USA;4. UCSF/UC Berkeley Joint Graduate Group in Bioengineering, San Francisco, CA, USA;1. Department of Orthopaedics, Leiden University Medical Center, The Netherlands;2. Department of Radiology, Leiden University Medical Center, The Netherlands;3. Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, The Netherlands;4. Mathematica institute Leiden University, Leiden University Medical Center, The Netherlands;5. C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, The Netherlands;1. Radiology and Biomedical Imaging, University of California,San Francisco, San Francisco, United States;2. University of California, Berkeley; San Francisco, United States;3. Veterans Affairs Medical Center, San Francisco, United States |
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| Abstract: | PurposeTo develop a RF coil system for joint imaging of intracranial and extracranial arterial vessel wall at 3T.Materials and methodThe coil system consists of a 24-channel head coil combined with an 8-channel carotid coil. It is compared with a standard coil configuration (12-channel head coil + 4-channel neck coil + 8-channel carotid coil) for SNR and g-factors in phantoms and healthy volunteers. The clinical relevance of the proposed coil system is also evaluated in patients.ResultsIn phantom experiments, the SNR of the proposed coil system is 53% higher than the maximum SNR of the standard coil configuration at the center of the phantom which usually corresponds to the intracranial region of the head. The g-factors of the proposed coil system in the sagittal plane are lower than the standard coil configuration (by 10.8% and 26.6% for R = 2 and 4 respectively) in the same experiment. In healthy volunteer experiments, 55% of the pixels have SNR above 100 for the proposed coil system, which is 33% more than that of the standard coil configuration. The maximum g-factors in the standard configuration are higher than those from the new coil design by 12% at R = 2 and up to 36% at R = 4 in the sagittal plane. In patients, in-vivo intracranial and extracranial arterial wall images at an isotropic spatial resolution of 0.6 mm can be acquired using the proposed coil system. Plaques are well depicted from the images.ConclusionsThe performance of the proposed coil set is superior to the standard coil configuration, providing high SNR, low g-factor and good spatial coverage needed for simultaneous high resolution imaging of intracranial and extracranial arterial walls. Images acquired in 7.6 min using the proposed coil system can achieve an isotropic spatial resolution of 0.6 mm and can be used to depict plaques on the intracranial and extracranial arterial walls in patients. |
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