3D high-resolution contrast enhanced MRI of carotid atheroma — a technical update期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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3D high-resolution contrast enhanced MRI of carotid atheroma — a technical update

Authors:	Chengcheng Zhu Umar Sadat Andrew J Patterson Zhongzhao Teng Jonathan H Gillard Martin J Graves

Institution:	1. University Department of Radiology, University of Cambridge, Cambridge, CB2 0QQ, UK;2. Vascular Surgery Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK

Abstract:	Objective Development of a fast 3D high-resolution magnetic resonance imaging (MRI) protocol for improved carotid artery plaque imaging. Methods Two patients with carotid atherosclerosis disease underwent 3D high-resolution MRI which included time-of-flight and T₁-weighted variable flip angle, fast-spin-echo (FSE) imaging, pre- and post-intravenous gadolinium-based contrast agent administration. Results Good quality images with intrinsic blood suppression were obtained pre- and post-contrast administration using a 3D FSE sequence. The plaque burden, lipid core volume, hemorrhage volume and fibrous cap thickness were well determined. Conclusions 3D high-resolution MR imaging of carotid plaque using TOF and 3D FSE can achieve high isotropic resolution, large coverage, and excellent image quality within a short acquisition time.

Keywords:	Carotid atheroma 3D Fast Spin Echo Lipid core Hemorrhage Fibrous cap
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