基于声学扫描振镜的超声/光声双模态成像技术

超声/光声双模态成像技术因其同时兼具超声的高分辨率结构成像和光声的高对比度功能成像优势,极大地推动了光声成像技术的临床应用推广.传统超声/光声双模态成像技术多基于超声成像所用阵列探头同时收集光声信号,系统结构紧凑且无需图像配准,操作便捷.但该类设备使用阵列探头和多通道数据采集,使得其成本较高;且成像结果易受通道一致性差异影响.本文提出了一种基于声学扫描振镜的超声/光声双模态成像技术,该技术采用单个超声换能器结合一维声学扫描振镜进行快速声束扫描,实现超声/光声双模态成像,是一种小型化、低成本的双模态快速成像技术.本文开展了系列仿体和活体成像研究,实验结果表明:系统有效成像范围为15.6 mm,超声和光声成像B扫描速度分别为1.0 s^–1和0.1 s^–1 (光声成像速度主要受制于脉冲激光器重复频率).基于本文所提技术研究,有助于进一步推动超声/光声双模态成像技术的临床转化和普及;也为基于超声信号检测的多模态成像技术提供了一种低成本、小型化和快速声信号检测的参考方案.

Ultrasound/photoacoustic dual-modality imaging based on acoustic scanning galvanometer

Ultrasound/photoacoustic dual-modality imaging technology has greatly promoted the clinical application and photoacoustic imaging technology because it integrates the advantages of high-resolution structural imaging of ultrasound and high-contrast functional imaging of photoacoustic imaging.Traditional ultrasound/photoacoustic dual-modality imaging is based mainly on the array probe used in ultrasound imaging to collect photoacoustic signals at the same time.The system has a compact structure and easy operation.However,this kind of equipment utilizes array probes and multi-channel data acquisition system,which makes it expensive.And the imaging quality can be affected by the difference in channel consistency.In this paper,an ultrasound/photoacoustic dual-modality imaging method based on an acoustic scanning galvanometer is proposed.In this system,a single ultrasonic transducer combined with a one-dimensional acoustic scanning galvanometer is used for fast acoustic beam scanning to realize ultrasound/photoacoustic dual-modality imaging.It is a compact,low-cost and fast dual-modality imaging technology.The experimental results show that the effective imaging range of the system is 15.6 mm,and the temporal resolution of ultrasound and photoacoustic imaging are 1.0 and 0.1 s^–1(B scan),respectively(the temporal resolution of photoacoustic imaging is limited mainly by the laser repetition rate).Based on the proposed technology research,it is helpful to further promote the clinical transformation and popularization of ultrasound/photoacoustic dual-modality imaging.It also provides a low-cost,miniaturized and fast scheme for multimodal imaging technology which is based on ultrasound signal detection.