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Detection system for singlet oxygen luminescence in photodynamic therapy |
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| Authors: | Buhong Li Huiyun Lin Defu Chen Min Wang Shusen Xie Key Laboratory of Optoelectronic Science Technology for Medicine Ministry of Education of China Fujian Provincial Key Laboratory for Photonics Technology Fujian Normal University Fuzhou China |
| Institution: | Buhong Li Huiyun Lin Defu Chen Min Wang , Shusen Xie Key Laboratory of Optoelectronic Science , Technology for Medicine,Ministry of Education of China,Fujian Provincial Key Laboratory for Photonics Technology,Fujian Normal University,Fuzhou 350007,China |
| Abstract: | Singlet oxygen(~1O_2) is widely considered to play a major role in photodynamic therapy(PDT),and thus an increasing attention has been focused on the direct detection of ~1O_2 near-infrared luminescence around 1270 nm for PDT dosimetry.A new sensitive detection system is developed to directly measure the temporal and spectral resolved ~1O_2 luminescence spectra.The triplet state and ~1O_2 lifetimes of Rose Bengal as a model photosensitizer in different solvents are determined,and the obtained results agree ... |
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