THE 31P NMR INVESTIGATION OF PHOSPHORUS BURNS

PurposeIn order to investigate the chemical form and distribution of toxicants absorbed following phophorus burns(PB). MethodsSurface-coil ³¹P NMR was used to study the contents of phosphorus (P₄) and its metabolites in liver, brain and wounds after PB, Phosphate scald (PS), and subcutaneous injection of phosphorus (SIP). ResultsObvious sign of P₄ in the liver but not brain was observed in both dead and survival animals following SIP. While after PB most P₄ was changed into phosphate, phosphate increased significantly in the liver and mild in the brain with no sign of P₄ after PB and PS. Conclusion The chemical form of main toxicants absorbed was accompaned with those remained within wounds after PB. Phosphoric acid was fetal cause of phosphorus poisoning after PB.