| 新型连翘脂素-布洛芬酯合物的波谱学数据解析 |
| |
| 引用本文： | 樊宏宇.新型连翘脂素-布洛芬酯合物的波谱学数据解析[J].波谱学杂志,2018,35(1):98-108. |
| |
| 作者姓名： | 樊宏宇 |
| |
| 作者单位： | 大连富生天然药物开发有限公司,辽宁大连116000;辽宁省中药单体原料及制剂工程技术研究中心,辽宁大连116000 |
| |
| 基金项目： | 大连市科技计划资助项目(2010E12SF068) |
| |
| 摘 要： | 以连翘脂素和布洛芬为原料，通过Schotten-Baumann酯化合成了酯合物——连翘脂素-布洛芬酯.对其紫外吸收光谱（UV）、红外吸收光谱（IR）、基质辅助激光解吸/电离飞行时间质谱（MALDI-TOF-MS）、1D和2D核磁共振（NMR）波谱（包括1H NMR、13C NMR、DEPT、1H-1H COSY、1H-1H NOESY、1H-13C HSQC和1H-13C HMBC）进行了解析，对其1H和13C NMR谱峰进行了全归属.
|
| 关 键 词： | 核磁共振(NMR) 连翘脂素 布洛芬 红外吸收光谱(IR) 紫外吸收光谱(UV) |
| 收稿时间： | 2017-06-13 |
Spectral Analyses of a Novel Ibuprofen-Phillygenin Ester |
| |
| FAN Hong-yu.Spectral Analyses of a Novel Ibuprofen-Phillygenin Ester[J].Chinese Journal of Magnetic Resonance,2018,35(1):98-108. |
| |
| Authors: | FAN Hong-yu |
| |
| Institution: | 1. Dalian Fusheng Natural Pharmaceutical Co., Ltd., Dalian 116000, China;2. Liaoning API and Formulation of Traditional Chinese Medicine Monomer Engineering Technology Research Center, Dalian 116000, China |
| |
| Abstract: | An ibuprofen-phillygenin ester was synthesized through the Schotten-Baumann reaction with ibuprofen and phillygenin as the starting materials.Ultraviolet absorption (UV) spectrum,infrared absorption (IR) spectrum,matrix-assisted laser desorption/ionization-mass spectra (MALDI-TOF-MS),and one-dimensional/two dimensional nuclear magnetic resonance (NMR) spectra (i.e.,1H-NMR,13C-NMR,13C-DEPT,1H-1H COSY,1H-1H NOESY,1H-13C HSQC and 1H-13C HMBC) of the compound were collected.All 1H and 13C NMR signals were assigned. |
| |
| Keywords: | NMR phillygenin ibuprofen infrared absorption spectrum (IR) ultraviolet absorption spectrum (UV) |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《波谱学杂志》浏览原始摘要信息 |
| 点击此处可从《波谱学杂志》下载免费的PDF全文 |
