| 海洋真菌中Actinopyrone A and C的分离与结构解析 |
| |
| 引用本文： | 李想,姚燕华,郑毅男,林文翰,ISABEL Sattler.海洋真菌中Actinopyrone A and C的分离与结构解析[J].波谱学杂志,2007,24(3):275-280. |
| |
| 作者姓名： | 李想 姚燕华 郑毅男 林文翰 ISABEL Sattler |
| |
| 作者单位： | 吉林农业大学,中药材学院,吉林,长春,130118;北京大学,天然药物与仿生药物国家重点实验室,北京,100083;Hans-Kn(o)ll-Institute for Natural Product Research,Beutenbergstraβe 11,D-07745,Jena,Germany;吉林农业大学,中药材学院,吉林,长春,130118;北京大学,天然药物与仿生药物国家重点实验室,北京,100083;Hans-Kn(o)ll-Institute for Natural Product Research,Beutenbergstraβe 11,D-07745,Jena,Germany |
| |
| 基金项目： | This project is part of a collaboration between the Hans-Kn(o)ll -Institute for Natural Product Research (HKI) and the National Research Laboratory of Natural and Biomimetic Drugs;; |
| |
| 摘 要： | 应用各种层析手段（Sephadex LH-20，硅胶Silica和RP-8柱层析），从海洋真菌发酵液中分离纯化了2个actinopyrone类化合物，结合多种波谱方法（HRESI-MS, 1D NMR, 2D NMR），确定了它们的结构为：actinopyrone A 和 C. 利用NOESY试验确定了它们的相对构型，并根据HMBC数据纠正了这2个化合物C-21（H-21）位和C-22（H-22）位的化学位移.
|
| 关 键 词： | NMR 结构解析 海洋真菌 actinopyrone A actinopyrone C |
| 文章编号： | 1000-4556（2007）03-0275-06 |
| 收稿时间： | 2006-10-18 |
| 修稿时间： | 2006-10-182007-03-19 |
Structure Elucidation of Actinopyrone A and C Isolated from Marine Fungus Penicillium sp. |
| |
| LI Xiang,YAO Yan-hua,ZHENG Yi-nan,LIN Wen-han,ISABEL Sattler.Structure Elucidation of Actinopyrone A and C Isolated from Marine Fungus Penicillium sp.[J].Chinese Journal of Magnetic Resonance,2007,24(3):275-280. |
| |
| Authors: | LI Xiang YAO Yan-hua ZHENG Yi-nan LIN Wen-han ISABEL Sattler |
| |
| Institution: | Pharmaceutical College, Jilin Agricultural University, Changchun, 130118 China |
| |
| Abstract: | Two antibiotic compounds, actinopyrone A (1) and C (2) were separated from lyophilized culture broth of marine fungus Penicillium sp. and their structures were elucidated with 1D and 2D NMR and HR-ESI-MS. The relative stereochemistry of compounds 1 and 2 was determined by analyzing the NMR NOESY data. Based on the NMR HMBC data, the erroneous chemical shifts of C-21 (H-21) and C-22 (H-22) reported in the literature were corrected. |
| |
| Keywords: | NMR structure elucidation actinopyrone marine fungus |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《波谱学杂志》浏览原始摘要信息 |
| 点击此处可从《波谱学杂志》下载免费的PDF全文 |
|
