| 2-酮基-L-古龙酸结构发生改变的核磁共振研究 |
| |
| 引用本文： | 安志敏,马二倩,杨秋青.2-酮基-L-古龙酸结构发生改变的核磁共振研究[J].波谱学杂志,2014,31(3):407-414. |
| |
| 作者姓名： | 安志敏 马二倩 杨秋青 |
| |
| 作者单位： | 河北师范大学 化学与材料科学学院，分析测试中心，河北 石家庄 050024 |
| |
| 基金项目： | 河北师范大学自然科学基金资助项目(L2011Y09) |
| |
| 摘 要： | 发现并揭示了2-酮基-L-古龙酸在许多种溶剂中发生了结构改变,该物质在室温条件下,无需施加任何外力因素,分子中极易发生分子内成环结构变化:分子中的羰基(-C=O)双键断开变单键,形成了2,5位半缩醛五元环衍生物,使分子内出现了O-C-O基团,其标题化合物的核磁共振碳谱(13C NMR)羰基特征峰的化学位移(约200)变到了96,核磁共振2D HMBC异核相关谱,充分证明了2-酮基-L-古龙酸发生的分子内环合成衍生物的主要产物是五元环的2,5位半缩醛衍生物,而非六元环的2,6位半缩醛衍生物.
|
| 关 键 词： | 液体核磁共振(liquid NMR) 结构变化 2D NMR 2-酮基-L-古龙酸 |
| 收稿时间： | 2013-10-11 |
Structural Changes of 2-Keto-L-Gulonic Acid Studied by NMR Spectroscopy |
| |
| AN Zhi-min,MA Er-qian,YANG Qiu-qing.Structural Changes of 2-Keto-L-Gulonic Acid Studied by NMR Spectroscopy[J].Chinese Journal of Magnetic Resonance,2014,31(3):407-414. |
| |
| Authors: | AN Zhi-min MA Er-qian YANG Qiu-qing |
| |
| Institution: | College of Chemistry and Material Science, Analysis and Testing Center, Hebei Normal University, Shijiazhuang 050024, China |
| |
| Abstract: | 2-keto-L-gulonic acid (2-KLG) changes its molecular structure in many solvents at room temperature. A five-membered intramolecular ring structure can easily be formed by the 2,5-hemiacetal reaction after the opening of the carbonyl group in 2-KLG (-C=O) to form a O-C-O interlinkage. In this study, we showed that the 13C chemical shift of the carbonyl changed fromδ 200 towards high field to aboutδ 96 after forming the intramolecular ring. Two-dimensional HMBC experiments revealed that 2-keto-L-gulonic acid formed five-membered ring 2,5-hemiacetal derivates in seven solvents, instead of
six-membered 2,6-hemiacetal derivates. |
| |
| Keywords: | liquid NMR structure changes 2D NMR 2-keto-L-gulonic acid |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《波谱学杂志》浏览原始摘要信息 |
| 点击此处可从《波谱学杂志》下载免费的PDF全文 |
|
