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The treatment of vocal fold paralysis with injectable collagen: Clinical concerns
Authors:Joseph R. Spiegel   Robert T. Sataloff  Wilbur James Gould
Abstract:Over the past several years, the treatment of vocal cord paralysis has been substantially improved by the availability of injectable Teflon. This substance, suspended in glycerin, has provided consistent results in laryngeal rehabilitation due to its tissue tolerance and lack of resorption. Recently, moified bovine collagen has been proposed as an additional substance for use in vocal cord injections to treat vocal fold paralysis. Collagen is currently being used for augmentation of dermatologic scarring, especially on the face. It has undergone clinical trials and has now been approved for clinical use in this setting. Bovine collagen has proven very useful in scar modification. The injections are generally well tolerated and adverse responses do not often occur. Most of the adverse local reactions can be avoided by using a skin test on the forearm 1 month prior to treatment and excluding those patients with positive responses.
Keywords:Vocal cord paralysis   Injectable collagen   Teflon   Laryngeal rehabilitation   Resorption   Antibody testing
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