| DNA分子力学性质的测量 |
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| 引用本文： | 冉诗勇,王艳伟,杨光参.DNA分子力学性质的测量[J].物理实验,2011,31(7):1-4. |
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| 作者姓名： | 冉诗勇 王艳伟 杨光参 |
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| 作者单位： | 温州大学物理与电子信息工程学院物理实验中心,浙江温州,325035 |
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| 基金项目： | 浙江省自然科学基金资助项目，温州大学研究生教改项目 |
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| 摘 要： | 利用单分子实验技术测量了DNA分子的力学性质.通过生化手段将单根DNA分子连在顺磁小球与玻璃侧壁之间,利用磁铁对顺磁球施加力进而拉伸DNA.图像分析得到小球运动的轨迹以及DNA的长度,利用均分定理可以求得施加的外力.测量发现在外力作用下DNA分子的力学反应与高分子物理学的蠕虫状链模型符合良好.
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| 关 键 词： | DNA 力学性质 单分子 均分定理 |
Measuring the elastic behavior of DNA |
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| RAN Shi-yong,WANG Yan-wei,YANG Guang-can.Measuring the elastic behavior of DNA[J].Physics Experimentation,2011,31(7):1-4. |
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| Authors: | RAN Shi-yong WANG Yan-wei YANG Guang-can |
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| Institution: | RAN Shi-yong,WANG Yan-wei,YANG Guang-can(Center for Physical Experiment,School of Physics and Electronic Information Engineering,Wenzhou University,Wenzhou 325035,China) |
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| Abstract: | The experiment on measuring the elastic behavior of DNA molecule using single molecule method was presented.A single DNA molecule was linked between a paramagnetic bead and the sidewall of a glass slide using biochemical method.The trajectory of the bead and the end-to-end length of the DNA molecule were obtained through image analysis.Then,the applied force was calculated according to equipartition theorem.It was found that the mechanic responses to forces agreed with worm-like-chain model well. |
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| Keywords: | DNA elastic behavior single molecule equipartition theorem |
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