兼具磁共振响应的碳量子点光致发光材料的构筑和性能

碳量子点作为光功能组分和纳米载体用于构筑磁共振-荧光双模态分子探针的研究才刚刚开始。本文首次以兼作Gd3+源和碳源的钆喷酸单葡甲胺为前驱体,研究了热裂解温度、保温时间和加热速率对前驱体碳化程度、所得产物量子产率和Gd3+掺杂量的影响。结果显示,前驱体在经历合理的热裂解条件(热裂解温度不高于350℃)后,可简便地制得Gd3+螯合物掺杂的碳量子点。该碳量子点除了具有优异的发光能力外(量子产率~7.6%),还表现出磁共振响应(纵向弛豫率~6.5 mmol-1·L·s-1),可用作磁共振-荧光双模态分子影像探针。

Preparation and Properties of Carbon Quantum Dots-photoluminescence Materials with Magnetic Resonance Response

The study of carbon quantum dots used as either photoluminescence functional components or nano carriers for magnetic resonance-fluorescence multimodal molecular imaging probe is just beginning. In the paper, the gadopentetate monomeglumine was used as a precursor which provides simultaneously carbon sources and Gd³⁺ sources. The influences of pyrolysis temperature, holding time and heating rate on the carbonization degree of the precursor, the quantum yield and the Gd³⁺ content of the products were studied. When the precursor was pyrolized under reasonable condition (the pyrolysis temperature was not higher than 350 ℃), Gd³⁺ chelates dopped carbon quantum dots were facilely prepared. The carbon quantum dots not only possessing high luminous power (quantum yield ~7.6%), but also showing good magnetic resonance response (longitudinal relaxation rate ~6.5 mmol^-1·L·s^-1) can be used as a magnetic resonance/fluorescence multimodal molecular imaging probe.