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Analysis of a Cahn–Hilliard–Brinkman model for tumour growth with chemotaxis
Authors:Matthias Ebenbeck  Harald Garcke
Institution:Fakultät für Mathematik, Universität Regensburg, 93040 Regensburg, Germany
Abstract:Phase field models recently gained a lot of interest in the context of tumour growth models. Typically Darcy-type flow models are coupled to Cahn–Hilliard equations. However, often Stokes or Brinkman flows are more appropriate flow models. We introduce and mathematically analyse a new Cahn–Hilliard–Brinkman model for tumour growth allowing for chemotaxis. Outflow boundary conditions are considered in order not to influence tumour growth by artificial boundary conditions. Existence of global-in-time weak solutions is shown in a very general setting.
Keywords:35K35  35Q92  92C50  35D30  76D07  Tumour growth  Cahn–Hilliard equation  Brinkman's law  Chemotaxis  Stokes flow  Outflow conditions
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