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Systems biology reveals biology of systems
Authors:Marta Bertolaso  Alessandro Giuliani  Laura De Gara
Institution:1. University Campus Bio‐Medico di Roma, Institute of Philosophy of the Scientific and Technological Activity, Rome, Italy;2. Environment and Health Department, Istituto Superiore di Sanità, Rome, Italy;3. Integrate Centre of Research, University Campus Bio‐Medico of Rome, Rome, Italy
Abstract:In the last decades, genomic and postgenomic technologies obtained a great amount of information on molecular bases of cell physiology and organization. In spite of this, the knowledge of cells and living organisms in their entirety, is far from being achieved. In order to deal with biological complexity, Systems Biology uses a new approach to overcome this inadequacy. Despite different definitions, Systems Biology's view of biological phenomena highlights that a holistic perspective is needed to integrate and understand the huge amount of empirical data which have been collected. This is one of the aspects that makes Systems Biology so interesting, from a theoretical and epistemological point of view, and that renders it a useful tool to help students approach living beings' dynamics within a comprehensive framework of their biological features as well. © 2010 Wiley Periodicals, Inc. Complexity, 2010
Keywords:systems biology  biological complexity  systemic perspective  theory formation  scientific activity
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