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Two new eremophilanolides from Xanthium sibiricum
Authors:Zhang Xiao-Qi  Ye Wen-Cai  Jiang Ren-Wang  Yin Zhi-Qi  Zhao Shou-Xun  Mak Thomas C W  Yao Xin-Sheng
Institution:Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632, PR China.
Abstract:Two new eremophilanolides, sibiriolides A (1) and B (2), were isolated from the aerial parts of Xanthium sibiricum. The structures of the new compounds were identified as 4S,5R,7R,8R, 11R-2-oxo-1(10)-eremophilen-12,8-olide (1) and 4S,5R,7R,8R,11S-2-oxo-1(10)-eremophilen-12,8-olide (2) by HREIMS and NMR spectroscopic techniques in combination with X-ray crystallographic analysis and CD measurements.
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