Intramolecular iodoetherification of ene or diene ketals: facile synthesis of spiroketals |
| |
| Authors: | Fujioka Hiromichi Nakahara Kenji Hirose Hideki Hirano Kie Oki Tomohiro Kita Yasuyuki |
| |
| Institution: | Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, 565-0871, Japan. fujioka@phs.osaka-u.ac.jp |
| |
| Abstract: | A novel and rapid approach to chiral mono- or di-substituted spiroketals based on remote asymmetric induction by intramolecular iodoetherification of ene or diene ketals has been developed. This strategy concisely offers 5,5- and 5,6-spiroketals including the natural insect pheromone of the wasp. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
