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Benzosceptrin C, a new dimeric bromopyrrole alkaloid from sponge Agelas sp. |
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| Authors: | Takaaki Kubota,Tetsuro Yasuda,Jane Fromont,Yuzuru Mikami,Jun&rsquo ichi Kobayashi |
| Affiliation: | a Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan b Western Australian Museum, Locked Bag 49, Welshpool DC, WA 6986, Australia c Medical Mycology Research Center, Chiba University, Chiba 260-0856, Japan d Bruker BioSpin K. K., 3-9 Moriya, Kanagawa, Yokohama 221-0022, Japan |
| Abstract: | A new dimeric bromopyrrole alkaloid possessing a benzocyclobutane ring, benzosceptrin C (1), has been isolated from an Okinawan marine sponge of the genus Agelas (SS-956), and the structure and relative stereochemistry were elucidated from spectroscopic data. Benzosceptrin C (1) showed antimicrobial activity. |
| Keywords: | Sponge Agelas sp. Bromopyrrole alkaloids Benzosceptrin C |
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