瓜环与喹啉衍生物包结配合行为研究

利用¹H NMR以及荧光技术研究了六、七、八元瓜环与2-苯基喹啉、N-正丙基溴化异喹啉、3-氨基喹啉及7,8-苯并喹啉的相互作用.两种方法的考察结果均表明,2-苯基喹啉能与这3种瓜环发生相互作用,其中六、七元瓜环与2-苯基喹啉形成1∶1的稳定包结配合物,包结常数分别为1.6×10⁴和3.2×10³L/mol.八元瓜环能与2-苯基喹啉形成1∶2包结物.¹H NMR结果还表明,3种瓜环均能与N-正丙基溴化异喹啉相互作用,其化学计量比均为1∶2;七元瓜环与7,8-苯并喹啉相互作用,化学计量比约为1∶1.荧光法也表明八元瓜环能与N-正丙基溴化异喹啉、3-氨基喹啉及7,8-苯并喹啉发生相互作用,并且荧光强度随瓜环浓度增加而下降,其化学计量比为1∶2.同时,讨论了上述主客体包结配合物的作用模式.

Inclusion Complexing Behavior of Cucurbit[ n ]urils with Some Quinoline Derivatives

The interaction of cucurbit[n=6,7,8]urils(Q[6],Q[7],Q[8]) with some quinoline derivatives,such as 2-phenylquinoline,N-propylquinoline,3-aminoquinoline and 7,8-phenylquinoline,were studied by using ¹H NMR technique and fluorometric analysis.The experimental results of both methods reveal that 2-phenylquinoline can form stable inclusion complex with Q[6],Q[7],Q[8] with a ratio of 1∶1,1∶1 and 2∶1 respectively,and the inclusion constants of 2-phenylquinoline-Q[6] or Q[7] was 1.6×10⁴ and 3.2×10³ L/mol respectively.¹H NMR results also show that Q[6],Q[7],Q[8] could form inclusion complex with N-propylquinoline with a ratio of 2∶1 repectively,and Q[7] could form inclusion complex with 7,8-phenylquinoline with a ratio of 1∶1.Fluorometric analysis reveal that the host-guest complexes of Q[8] and the title quinoline derivatives were formed with a ratio of 1∶2 repectively,and the fluorescence of the interacted quinoline derivatives was queched by Q[8].Also the interaction models were suggested for the above hous-guest inclusion complexes.