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Embryotoxicity studies of tri‐n‐butyltin(IV) complexes of 5‐[(E)‐2‐(aryl)‐1‐diazenyl]‐2‐hydroxybenzoic acid and 2‐[(E)‐2‐(3‐formyl‐4‐hydroxyphenyl)‐1‐diazenyl] benzoic acid on sea urchin development |
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| Authors: | Tushar S Basu Baul Wandondor Rynjah Keisham Surjit Singh Claudia Pellerito Paolo D'Agati Lorenzo Pellerito |
| Abstract: | The toxicity studies of free 5‐(E)‐2‐(aryl)‐1‐diazenyl]‐2‐hydroxybenzoic acid and 2‐(E)‐2‐(3‐formyl‐4‐hydroxyphenyl)‐1‐diazenyl]benzoic acid and their tri‐n‐butyltin(IV) complexes were evaluated by using sea urchin early developmental stages as recommended model organisms for toxicity tests. The novel complexes, as the parent tri‐n‐butyltin(IV) chloride (TBTCl), caused mitosis block and induced high embryonic mortality in sea urchin. Copyright © 2005 John Wiley & Sons, Ltd. |
| Keywords: | tri‐n‐butyltin 5‐[(E)‐2‐(aryl)‐1‐diazenyl]‐2‐hydroxybenzoic acid 2‐[(E)‐2‐(3‐formyl‐4‐hydroxy phenyl)‐1‐diazenyl]benzoic acid sea urchins toxicity |