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Palladium‐Catalyzed Carbonylative Reactions of 1‐Bromo‐2‐fluorobenzenes with Various Nucleophiles: Effective Combination of Carbonylation and Nucleophilic Substitution |
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| Authors: | Jianbin Chen Dr Kishore Natte Dr Helfried Neumann Prof Xiao‐Feng Wu |
| Institution: | Leibniz‐Institut für Katalyse an der Universit?t Rostock e.V. Albert‐Einstein‐Str. 29a, 18059 Rostock (Germany) |
| Abstract: | A systematic study on the carbonylative transformation of 1‐bromo‐2‐fluorobenzenes with various nucleophiles has been performed. Different types of double nucleophiles, such as N?N, N?C, O?C, and N?S, can be effectively applied as coupling partners. The corresponding six‐membered heterocycles were isolated in moderate to good yields. |
| Keywords: | carbonylation domino reactions heterocycles nucleophilic substitution palladium |