EQUIP: a worldwide program to ensure the quality of urinary iodine procedures |
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| Authors: | Kathleen L Caldwell Amir Makhmudov Robert L Jones Joseph G Hollowell |
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| Institution: | (1) Inorganic Toxicology and Nutrition Branch, Division of Laboratory Sciences, National Center for Environmental Health, CDC, 4770 Buford Highway, NE, Mail Stop F18, Atlanta, GA 30341, USA;(2) Department of Pediatrics, University of Kansas Medical Center, 435 N. 1500 Road, Lawrence, KS 66049, USA |
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| Abstract: | In 2001 the Centers for Disease Control and Prevention (CDC) established a program, Ensuring the Quality of Urinary Iodine
Procedures (EQUIP); to assist laboratories around the world and assess the accuracy of their urinary iodine (UI). CDC designed
EQUIP to issue unknown specimens to participating laboratories three times per year. Each laboratory was asked to analyze
unknown samples in duplicate on three different days. During the first five rounds of EQUIP, 41 laboratories participated,
measuring unknown samples and reporting their results to CDC. CDC used these results to prepare a statistical report for the
laboratories. Feedback to the laboratories provided external confirmation regarding performance. As a group, laboratory performance
improved; several laboratories made considerable improvement. Several laboratories that showed no improvement have ordered
new equipment or are arranging for additional training. EQUIP is a key tool used to support laboratory quality assurance in
an effort to eliminate iodine deficiency disorders (IDD) in the world.
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| Keywords: | Urinary iodine Iodine deficiency disorders Laboratory testing ICP-MS Laboratory proficiency Laboratory methods |
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