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相似系统理论定量评价中药材色谱指纹图谱的相似度
引用本文:刘永锁,曹敏,王义明,罗国安.相似系统理论定量评价中药材色谱指纹图谱的相似度[J].分析化学,2006,34(3):333-337.
作者姓名:刘永锁  曹敏  王义明  罗国安
作者单位:1. 清华大学分析中心,北京,100084
2. 中国药科大学分析化学教研室,南京,210009
基金项目:国家科技部“十五”攻关项目(No.2004BA721AB、No.2002B906A29-3),国家自然科学基金重点项目(No.9020005)资助
摘    要:研究相似系统理论定量评价中药材提取物液相色谱指纹图谱的相似度。以相似系统理论对栀子药材提取物高效液相色谱指纹图谱的相似度评价,发现相似系统理论对数据的差异比较敏感,而且相似度的计算结果能够反映样品的相对差异。相似系统理论可以作为一种评价中药色谱指纹图谱相似度的新方法。

关 键 词:中药指纹图谱  相似度  相似系统理论  程度相似度  数量相似度
收稿时间:05 25 2005 12:00AM
修稿时间:2005-05-252005-08-30

Similarity System Theory to Evaluate the Similarity of High Performance Liquid Chromatography Fingerprint of Traditional Chinese Medicine Quantitatively
Liu Yongsuo,Cao Min,Wang Yiming,Luo Guoan.Similarity System Theory to Evaluate the Similarity of High Performance Liquid Chromatography Fingerprint of Traditional Chinese Medicine Quantitatively[J].Chinese Journal of Analytical Chemistry,2006,34(3):333-337.
Authors:Liu Yongsuo  Cao Min  Wang Yiming  Luo Guoan
Institution:Analysis Center,Tsinghua University,Beijing 100084;2.Department of Analytical Chemistry,China Pharmaceutical University, Nanjing 210009
Abstract:To study the similarity evaluation method of high performance liquid chromatography (HPLC) fingerprints of traditional Chinese medicine. The Similarity System Theory was proposed to calculate the similarity of HPLC fingerprints of the extracts of Fructus Gardiniae. It is sensitive and can reflect the relative differences of peak areas. Similarity System Theory can be used as a new method to evaluate the similarity of HPLC chromatographic fingerprints of traditional Chinese medicine.
Keywords:Traditional chinese medicine fingerprint  similarity  similarity system theory  extent similarity  numerical similarity
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