Regioselective Synthesis of 1,3,5-Trisubstituted Pyrazoles |
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| Authors: | Vidya G. Desai Pooja C. Satardekar Sampada Polo Kashinath Dhumaskar |
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| Affiliation: | 1. Department of Chemistry , Dnyanprassarak Mandal's College of Arts, Science, and Commerce , Goa , India vidchem@gmx.net;3. Department of Chemistry , Dnyanprassarak Mandal's College of Arts, Science, and Commerce , Goa , India |
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| Abstract: | ![]()
Abstract A new and a simple approach toward synthesis of 1,3,5-trisubstituted pyrazoles from chalcone arylhydrazones via oxidative cyclization has been achieved. 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone was successfully used as an oxidizing agent to give excellent yields of pyrazoles. |
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| Keywords: | Chalcones hydrazones oxidative cyclization pyrazoles regioselective |
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