Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents |
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| Authors: | Serrano M Concepción Gutiérrez María C Jiménez Ricardo Ferrer M Luisa del Monte Francisco |
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| Affiliation: | Instituto de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigaciones Científicas (CSIC), Cantoblanco 28049, Madrid, Spain. conchi.serrano@icmm.csic.es |
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| Abstract: | ![]()
Poly(octanediol-co-citrate) elastomers containing high loading of lidocaine were synthesized at temperatures below 100 °C by means of using deep eutectic mixtures of 1,8-octanediol and lidocaine. The preservation of lidocaine integrity resulted in high-capacity drug-eluting elastomers. |
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