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Diversity-oriented synthesis of amino acids using chiral enolates
Authors:Subhabrata Sen  Siva R. KammaVenkata R. Potti  Y.L.N. Murthy  Avinash B. Chaudhary
Affiliation:a GVK Bioscience, 28A IDA Nacharam, Hyderabad, India
b Department of Chemistry, Food, Drugs and Water, College of Science and Technology, Andhra University, Vishakhapatnam, India
Abstract:We report a facile diversity oriented synthesis of α- and β-amino acids, by utilizing the pluripotent α-methylene group in a chiral bicyclic lactam as our key point of transformation.
Keywords:Diversity oriented synthesis   α-Amino acid   β-Amino acid   Mannich reaction   Pluripotent functional group
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