| 合成多肽疫苗研究进展 |
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| 引用本文： | 许家喜. 合成多肽疫苗研究进展[J]. 高等学校化学学报, 2000, 21(11): 1688-1693 |
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| 作者姓名： | 许家喜 |
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| 作者单位： | 北京大学化学与分子工程学院,北京,100871 |
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| 基金项目： | 国家自然科学基金! (批准号 :2 9772 0 0 2 )资助 |
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| 摘 要： | 综述了合成多肽疫苗的研究进展,系统地介绍了目前寻找抗原肽的各种方法以及各类可用作疫苗接种的合成多肽抗原的制备和应用.
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| 关 键 词： | 多肽疫苗 抗原肽 佐剂 |
| 收稿时间： | 2000-01-21 |
Progress in Synthetic Peptide Vaccine |
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| XU Jia-Xi. Progress in Synthetic Peptide Vaccine[J]. Chemical Research In Chinese Universities, 2000, 21(11): 1688-1693 |
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| Authors: | XU Jia-Xi |
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| Affiliation: | College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China |
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| Abstract: | Research progress in synthetic peptide vaccine has been reviewed. Various methods seeking for epitopic peptides, including enzyme hydrolysis and chemical cleavage, deductive method aided by computer, chemically synthetic peptide method and X ray crystal structure, were discussed. Preparation methods and applications of various synthetic peptide antigens such as peptide carrier complex antigen, polymeric peptide antigen, etc, used in vaccination recently have been introduced systematically. |
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| Keywords: | Peptide vaccine Autigenic peptide Adjuvant |
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