New Ruthenium(II) Complexes Functionalized with Coumarin Derivatives: Synthesis,Energy‐Transfer‐Based Sensing of Esterase,Cytotoxicity, and Imaging Studies |
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| Authors: | Dr Mei‐Jin Li Dr Keith Man‐Chung Wong Dr Changqing Yi Prof Vivian Wing‐Wah Yam |
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| Institution: | 1. Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR (P.R. China);2. Key Laboratory of Analysis and Detection Technology for Food Safety (Ministry of Education and Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108 (P.R. China);3. School of Engineering, Sun Yat‐Sen University, Guangzhou 510275 (P.R. China) |
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| Abstract: | Two new bichromophoric ruthenium(II) complexes, Ru(bpy)2(bpy‐CM)](PF6)2 and Ru(bpy)2(bpy‐CM343)](PF6)2 (bpy=2,2′‐bipyridine, CM=coumarin) with appended coumarin ligands have been designed and synthesized. The energy‐transfer‐based sensing of esterase by the complexes has been studied by using UV/Vis and luminescence spectroscopic methods. The cytotoxicity and the cellular uptake of one of the complexes have also been investigated. |
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| Keywords: | coumarins energy transfer luminescence ruthenium |
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