Sodium 1‐Naphthalenesulfonate‐Functionalized Reduced Graphene Oxide Stabilizes Silver Nanoparticles with Lower Cytotoxicity and Long‐Term Antibacterial Activity |
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| Authors: | Dr Xiang Cai Prof Shaozao Tan Aili Yu Jinglin Zhang Jiahao Liu Prof Wenjie Mai Prof Zhenyou Jiang |
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| Institution: | 1. Department of Chemistry, Jinan University, Guangzhou 510632 (P. R. China), Fax: (+86)?20‐8522‐3670;2. Department of Physics, Jinan University, Guangzhou 510632 (P. R. China);3. Department of Microbiology and Immunology, Medical School of Jinan University, Guangzhou 510632 (P. R.China) |
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| Abstract: | Silver nanoparticles (AgNPs) are increasingly used in daily life for their antibacterial properties, but their low stability and high cytotoxicity hamper practical applications. In this work, sodium 1‐naphthalenesulfonate‐functionalized reduced graphene oxide (NA‐rGO) was used as a substrate for AgNPs to produce a AgNP‐NA‐rGO hybrid. This hybrid showed substantially higher antibacterial activity than polyvinyl pyrrolidone(PVP)‐stabilized AgNPs, and the AgNPs on NA‐rGO were more stable than the AgNPs on PVP, resulting in long‐term antibacterial effects. More importantly, this hybrid showed excellent water solubility and low cytotoxicity, suggesting the great potential application as sprayable reduced graphene oxide based antibacterial solutions. |
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| Keywords: | antibacterial properties cytotoxicity reduced graphene oxide nanoparticles silver |
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