The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction |
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| Authors: | Dai Chaofeng Wang Lifang Sheng Jia Peng Hanjing Draganov Alexander Boryanov Huang Zhen Wang Binghe |
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| Institution: | Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, Georgia 30302-4098, USA. |
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| Abstract: | The first chemical incorporation of the boronic acid group into DNA using a copper-free click reagent was reported. Compared with the PCR-based method, this approach allows for site-specific incorporation and synthesis on a larger scale. |
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